Together we’re better in treating persistent and long-standing persistent AF

View all Hy⁵ centers



What is Hy⁵?

Hybrid ablation (HA) combines the strengths of thoracoscopic surgical ablation and catheter-based endocardial ablation in a single treatment strategy.

Performed either as a single-stage or two-stage procedure, hybrid ablation allows clinicians to both create and validate lesions within the same pathway of care.

In a single-stage procedure, intraoperative electrophysiological mapping confirms the completeness of surgical lesions in real time. Any gaps can be immediately identified and treated, ensuring effective isolation. The left atrial appendage is also routinely closed as part of the procedure.

This collaborative approach enables a comprehensive treatment without the need for sternotomy or cardiopulmonary bypass.







How does Hy⁵ work?

Hy⁵ combines surgical ablation and electrophysiological validation into a single, coordinated pathway.

From pulmonary vein isolation through to ongoing monitoring, each step is designed to create, confirm and maintain durable lesions — reducing variability and improving consistency of outcomes.










Why is CS/EP collaboration essential?

No single approach can fully address complex atrial fibrillation.

By combining surgical access with electrophysiological insight, CS/EP collaboration enables more complete treatment — reducing the need for repeat procedures and improving the likelihood of durable success.


3-7x
repeat ablations often needed for long-standing AF¹
2x
success rate in hybrid approach²
73-80%
freedom from AF at 12 months in hybrid approach³


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Dr Geza Horvath
Cardiac surgeon

“When electrophysiologists and cardiac surgeons collaborate effectively, patient outcomes are significantly improved and more durable.”




Who is the Hy⁵ approach suitable for?

Dr M. Wehbe discusses the patient profile for the Hy⁵ procedure.




View all Hy⁵ centers

There are six Hy⁵ centers throughout Germany that treat this patient population using the Hy⁵ collaborative approach, within the heart team.

Refer your patient here